Four clients are receiving tyrosine kinase inhibitors (TKIs). Which of these four clients should the nurse assess first?
a. Client with dry, itchy, peeling skin
b. Client with a serum calcium of 9.2 mg/dL
c. Client with a serum potassium of 2.8 mEq/L
d. Client with a weight gain of 0.5 pound (1.1 kg) in 1 day
ANS: C
TKIs can cause electrolyte imbalances. This potassium level is very low, so the nurse should assess this client first. Dry, itchy, peeling skin can be a problem in clients receiving biologic response modifiers, and the nurse should assess that client next because of the potential for discomfort and infection. This calcium level is normal. TKIs can also cause weight gain, but the client with the low potassium level is more critical.
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