Marjorie takes an anti-anxiety drug so that she can sleep better and remain calm enough to study effectively. She begins by taking 25 milligrams every evening, but within a month this dose is no longer helping, so she takes two pills. After another month this dosage is no longer effective. This is happening because

A. she has developed tolerance, which means that her liver can no longer metabolize the drug, so it remains active for too long.
B. her immune system is rejecting the drug.
C. the number of receptors to which the drug binds on neurons has increased.
D. the number of receptors to which the drug binds on neurons has declined.


Answer: D

Anatomy & Physiology

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