The client receives methotrexate (Rheumatrex). The nurse assesses for side effects of this drug. Which side effects are a primary concern for the nurse?
1. Hyperglycemia and fatigue
2. Nausea and vomiting
3. Hypertension and seizures
4. Ulcerative stomatitis and diarrhea
4
Rationale 1: Hyperglycemia is not an adverse effect of methotrexate.
Rationale 2: Nausea and vomiting are expected adverse effects and are not the primary concern.
Rationale 3: Hypertension and seizures are not adverse effects of this drug.
Rationale 4: Ulcerative stomatitis and diarrhea require suspension of therapy because they may lead to hemorrhagic enteritis and death from intestinal perforation.
Global Rationale: Ulcerative stomatitis and diarrhea require suspension of therapy because they may lead to hemorrhagic enteritis and death from intestinal perforation. Hyperglycemia is not an adverse effect of methotrexate. Nausea and vomiting are expected adverse effects and are not the primary concern. Hypertension and seizures are not adverse effects of this drug.
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In ____________________, care is provided based on the strength of the evidence.
Fill in the blank(s) with the appropriate word(s).
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