The most frequent presenting signs of leukemia are related to bone marrow infiltration. The main symptoms are:

1. Anemia, infection, and bleeding.
2. Thrombocytopenia, headache, and abdominal pain.
3. Respiratory distress and pain.
4. Confusion and decreased peripheral vascular resistance.


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1. The normal bone marrow is replaced with abnormal cells, leading to decreased red blood cells and anemia. The risk of infection relates to the lack of white blood cells and the reduction in platelets of thrombocytopenia.
2. The normal bone marrow is replaced with abnormal cells, leading to decreased red blood cells, which causes ischemia and pain. The risk of infection relates to the lack of white blood cells and the reduction in platelets of thrombocytopenia. Headaches are not a common sign.
3. The normal bone marrow is replaced with abnormal cells, leading to decreased red blood cells, which causes pain. The patient rarely exhibits signs of respiratory distress.
4. Neurological issues and peripheral vascular resistance are rare.

Nursing

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