The nurse is preparing to administer a prototype drug to a client with myasthenia gravis. What will the nurse identify as characteristics of this medication?
Standard Text: Select all that apply.
1. It affects nicotinic acetylcholine synapses in skeletal muscle.
2. It is the prototype drug.
3. It does not cross the placenta.
4. It decreases peristalsis and causes bronchodilation.
5. It must be used with caution in heart failure.
Correct Answer: 1,2,5
Rationale 1: Pyridostigmine is used to treat myasthenia gravis and affects the nicotinic acetylcholine synapses in skeletal muscle.
Rationale 2: Pyridostigmine is a prototype drug.
Rationale 3: Pyridostigmine does cross the placenta.
Rationale 4: Pyridostigmine enhances peristalsis and causes bronchoconstriction.
Rationale 5: Pyridostigmine can cause bradycardia and should be used cautiously in clients with heart failure.
Global Rationale: Pyridostigmine is a prototype drugs used to treat myasthenia gravis and affects the nicotinic acetylcholine synapses in skeletal muscle. Pyridostigmine can cause bradycardia and should be used cautiously in clients with heart failure. Pyridostigmine does cross the placenta. Pyridostigmine enhances peristalsis and causes bronchoconstriction.
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