A patient has been taking chlorthalidone to treat hypertension. The patient's prescriber has just ordered the addition of spironolactone to the patient's drug regimen. Which statement by the patient indicates a need for further teaching?
a. "I should continue following the DASH diet when adding this drug."
b. "I should not take an ACE inhibitor when adding this drug."
c. "I will need to take potassium supplements when adding this drug."
d. "I will not experience a significant increase in diuresis when adding this drug."
ANS: C
Spironolactone is given in addition to thiazide diuretics to balance potassium loss caused by the thiazide diuretic. Patients should be advised against taking potassium supplements with spironolactone, because hyperkalemia can result. The DASH diet may be continued. ACE inhibitors are contraindicated because they promote hyperkalemia. Spironolactone does not significantly increase diuresis.
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