A mutation occurs in a gene that encodes a G1 cyclin, such that the protein is unable to bind to its CDK. How will this affect the cell cycle?
A. The cell will rapidly replicate its DNA and progress through mitosis, causing uncontrolled cell division, and leading to cancer.
B. The cell will replicate its DNA, but will be unable to progress through mitosis.
C. The cell will proceed thru mitosis without replicating its DNA.
D. The cell will proceed to the S phase, and DNA repair enzymes will repair the mutated cyclin when it replicates the DNA.
E. The cell will be stuck in G1 and will not advance through the cell cycle.
Answer: E
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