Discuss lymphomas.
What will be an ideal response?
Lymphomas are cancers that originate in the lymph cells and tissues of the body. There are two main types: Hodgkin lymphoma and non-Hodgkin lymphoma. Each of these main types has several subtypes. Most all lymphomas present the same way with painless, swollen lymph nodes, fever, unexplained weight loss, chest pain and night sweats.
Hodgkin lymphoma usually begins in the lymph nodes of the neck and chest although it can start in any lymph node of the body. The most common variant of this disease occurs primarily in younger adults in their 20's, although can occur at a younger or older age. The age-adjusted incidence rate for Hodgkin disease is 2.8 per 100,000 men and women per year. The most well known risk for this tumor is a past history of infection with Epstein Barr Virus (EBV), the virus that causes mononucleosis, but it is also associated with infection with the Human Immunodeficiency Virus (HIV).
Non-Hodgkin lymphoma (NHL) has many different subtypes and may start in any part of the lymph system. The age-adjusted incidence rate for non-Hodgkin lymphoma is 19.8 per 100,000 men and women per year. The risk of this disease increases with age with most cases occurring in persons over the age of 60, only about 800 cases per year occur in children up to 19 years of age. It tends to occur more frequently in whites than any other race or ethnicity and in males slightly more than females. Radiation exposure, either environmentally or as treatment for disease, increases the risk of development of NHL. Overall the 5 year survival rate for NHL is 67%, much lower than that of Hodgkin lymphoma.
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