A client has been severely depressed for several months and has failed to respond appreciably to treatment with selective serotonin reuptake inhibitors (SSRIs)
As a result, his psychiatrist has begun a course of monoamine oxidase inhibitors (MAOIs). The care team has been careful to monitor for what adverse effect related to excess tyramine?
A) Increased agitation
B) Hypertensive crises
C) Serotonin syndrome
D) Tardive dyskinesia
Ans: B
Feedback:
Normally, MAO breaks down tyramine; however, because MAOIs inhibit MAO, tyramine can accumulate in the bodies of clients taking these drugs and eating tyramine-containing foods at the same time. Tyramine also releases norepinephrine from nerve endings. These metabolic actions can precipitate a hypertensive crisis.
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Which statement would indicate to the nurse that a 35-year-old pregnant client and spouse understand the instructions regarding amniocentesis?
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