Mature T cells with cerebriform, clefted nuclei found in the skin and peripheral blood describe:
a. Hairy cells
b. Prolymphocytes
c. Lymphoblasts
d. Sézary cells
ANS: D
Sézary cells are found in the peripheral blood in Sézary syndrome, a variant of mycosis fungoides. This is the most common cutaneous lymphoma. The immunophenotype is similar to that of T cells found in the skin. The cells have a cerebriform, clefted nucleus.
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