While taking their daily walk, the nurse is asked by a neighbor what centric fusion (robertsonian) translocation means. She tells you that a family member has been diagnosed with this and is now afraid to have children
Given this diagnosis, what may be potential risks for her offspring?
A)
If chromosome 21 is involved, there is a high risk for producing a child with Down syndrome.
B)
Since the extremely short fragment only contains a small amount of genetic material, there should be no additional risk than the normal population.
C)
This translocation of genetic material places the child at high risk for having multiple limb abnormalities.
D)
Cleft lip with cleft palate is frequently associated with this translocation of genetic material.
Ans:
A
Feedback:
In centric fusion or robertsonian translocation, the break occurs near the centromere affecting the short arm in one chromosome (13 and 14 or 14 and 21 most commonly). The short fragment is usually lost during subsequent divisions. In this case, the person has only 45 chromosomes, but the amount of genetic material lost is small. Difficulty arises during meiosis. The chief clinical significance arises when the translocation carriers involve chromosome 21, which may produce a child with Down syndrome.
You might also like to view...
A nurse has been asked to prepare patient education for Spanish-speaking patients regarding diabetes. This information will be available to patients in the diabetes clinic. What is the primary goal for this patient education?
a. To reduce the legal liability of the clinic b. To teach Spanish-speaking patients some English c. To assist Spanish-speaking patients to reach optimal health d. To provide information so they can make a decision between oral and injectable medications
A nurse has decided to pursue a DNP degree instead of a DNS degree. What are some basic differences between the DNP and DNS? (Select all that apply.)
A) Less emphasis on scientific content B) Increased content on research methodology C) Similar dissertation requirements D) Emphasis on practice with research E) No required clinical practicum
The integumentary system has several important functions in the body. They include all of the following except
A. preventing water loss B. producing chemicals to develop into vitamin D C. enhancing bacterial invasion D. regulating temperature
The Occupational Safety and Health Administration (OSHA)
A. inspects quarterly for fire safety. B. is responsible for employee safety. C. protects patients. D. monitors controlled substances.