A client is to be treated for an overdose of propranolol (Inderal). Which medications should the nurse anticipate being used?
Standard Text: Select all that apply.
1. Prazosin
2. Isoproterenol
3. Atropine
4. Metoprolol
5. Digoxin
Correct Answer: 2,3,5
Rationale 1: Prazosin (Cardura) is a selective alpha1-antagonist drug and is not used to treat overdose of propranolol (Inderal).
Rationale 2: Isoproterenol is an adrenergic agonist that is used to treat overdose of propranolol to reverse the bronchoconstriction.
Rationale 3: Atropine is an anticholinergic drug that is used to treat overdose of propranolol to reverse the severe bradycardia.
Rationale 4: Metoprolol is a selective beta1-adrenergic antagonist and has actions similar to propranolol, so it cannot be used for treating overdose of this drug.
Rationale 5: Cardiac failure caused by beta antagonist overdose can be treated by administering digoxin (Lanoxin) or diuretics.
Global Rationale: Isoproterenol is an adrenergic agonist that is used to treat overdose of propranolol to reverse the bronchoconstriction. Atropine is an anticholinergic drug that is used to treat overdose of propranolol to reverse the severe bradycardia. Cardiac failure caused by beta antagonist overdose can be treated by administering digoxin (Lanoxin) or diuretics. Prazosin (Cardura) is a selective alpha1-antagonist drug and is not used to treat overdose of propranolol (Inderal). Metoprolol is a selective beta1-adrenergic antagonist and has actions similar to propranolol, so it cannot be used for treating overdose of this drug.
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