Sudan black is used to distinguish which types of leukemia?

a. Acute myeloid leukemia from acute lymphoblastic leukemia
b. Acute myeloid leukemia from chronic myelogenous leukemia
c. Acute myeloid leukemia from acute promyelocytic leukemia
d. Acute promyelocytic leukemia from acute myelomonocytic leukemia


ANS: A
Lymphoid cells are generally negative, whereas myeloblasts are positive. Thus a positive result with this stain can be used to differentiate acute myeloid leukemia from acute lymphoblastic leukemia. The entire myeloid series through neutrophils is positive, so it is not useful in differentiating different types of acute myeloid leukemia. Monocytes are negative to weakly positive.

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