Which of the following most accurately describes how foreign substances can activate complement?
A. Foreign proteins are phagocytized by macrophages and directly activate complement.
B. Foreign substances can bind to spontaneously activated C3 and stabilize it.
C. Both "Antibodies can bind to foreign antigens and activate complement through the classical pathway" and "Foreign substances can bind to spontaneously activated C3 and stabilize it" are correct.
D. Foreign proteins bind to C1 and activate it.
E. Antibodies can bind to foreign antigens and activate complement through the classical pathway.
Answer: C
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