What is the major difference in the termination stage of translation between prokaryotes and eukaryotes?
A. There are two termination factors in prokaryotes (RF1 and RF2) and only one factor in eukaryotes (eRF).
B. There is no stop codon in prokaryotes while a stop codon is necessary in eukaryotes.
C. Ribosomal subunits dissociate in prokaryotes, but remain intact in eukaryotes.
D. There is one stop codon in prokaryotes (UAG) and three in eukaryotes (UAA, UAG, UGA).
E. mRNA remains connected to the small ribosomal subunit (30S) in prokaryotes, but is released from the small ribosomal subunit (40S) in eukaryotes.
Answer: A
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