A 72-year-old woman has been diagnosed with osteoporosis and has begun taking alendronate (Fosamax). The nurse should be aware that this drug can increase the woman's bone density by which of the following means?
A) Decreasing renal excretion of calcium
B) Increasing the binding of vitamin D to calcium ions
C) Suppressing the function of osteoclasts
D) Enhancing the function of osteoblasts
C
Feedback:
Alendronate suppresses osteoclast activity on newly formed resorption surfaces, which reduces bone turnover. This means that bone formation exceeds resorption at remodeling sites, leading to progressive gains in bone mass. Fosamax does not enhance osteoblast function or affect the renal excretion of calcium. It does not influence the chemical interaction between vitamin D and calcium.
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