A patient with rheumatic fever develops a sore throat from which betahemolytic streptococci are cultured. The patient is started on treatment with penicillin, and the sore throat resolves within several days. However, 7 days after initiation of penicillin therapy the patient develops a fever of 39.5°C, a generalized rash, and proteinuria. This MOST probably resulted from:
a. recurrence of the rheumatic fever
b. a different infectious disease
c. an IgE response to penicillin
d. an IgG-IgM response to penicillin
e. a delayed hypersensitivity reaction to penicillin
d. an IgG-IgM response to penicillin
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