If the human egg has 3 billion base pairs, how many nucleosomes will be present in the nucleus of a human somatic cell?
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In humans, the DNA wrapped around each nucleosome is approximately 200 bp (147 bp + 53 bp linker). As such, there will be approximately 3 × 109/2 × 102 = 1.5 × 107 nucleosomes in a human egg nucleus. However, the egg is haploid, whereas the somatic cells are diploid. Therefore, there will be approximately 1.5 × 107 × 2 = 3 × 107 nucleosomes in the nucleus of a human somatic cell.
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What will be an ideal response?