A patient is taking sertraline (Zoloft). Because of the danger of toxicity, the nurse advises the patient to avoid which food?
1. Milk
2. Peanuts
3. Grapefruit
4. Orange juice
Answer: 3
Explanation: Grapefruit is an inhibitor of CYP450-3A4, which affects the metabolism of a sertraline (Zoloft), which could potentially build up to toxic levels. Although certain individuals may be sensitive to peanuts or dairy products, these foods have not been associated with increasing the toxicity of Zoloft. Orange juice may be taken as a citrus alternative to grapefruit juice.
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