Distribution is concerned with which of the following activities of medications?
a. movement of a medication from blood to interstitial spaces and then into cells, and the amount of medication in various areas
b. speed at which medications move through the body and out of the body
c. route of administration of the medications and the area of the body there metabolism of the medication mainly takes place
d. which children the medication has been given to in order to facilitate studies of untoward effects and allergic reactions
A
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A Correct. Distribution is concerned with the movement or transport of drugs throughout the body (i.e., the process by which drugs are made available to body fluids and tissues). Factors influencing drug distribution in the body include body composition and fluid distribution, protein binding, blood flow to the tissues, and special membrane barriers.
B Incorrect. Distribution is not concerned with the speed at which medications move through the body and out of the body.
C Incorrect. Distribution is not concerned with the route of administration of the medications and the area of the body there metabolism of the medication mainly takes place.
D Incorrect. Distribution is not concerned with which children the medication has been given to in order to facilitate studies of untoward effects and allergic reactions.
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