A patient is admitted with glomerulonephritis. IV gentamicin therapy is started after cultures indicate gram-negative bacilli in the blood. The patient also receives IV furosemide (Lasix)
The nurse will monitor for signs and symptoms of toxicity related to which organ?
a. Kidneys
b. Pancreas
c. Liver
d. Brain
ANS: A
The results of urinalysis and kidney function tests should be closely monitored when a patient is on aminoglycoside therapy. Patients also receiving cephalosporins, enflurane, methoxyflurane, vancomycin, and diuretics, when combined with aminoglycosides, have a greater potential for nephrotoxicity. The pancreas is not vulnerable to damage from aminogylcosides. Bone marrow suppression is a result of toxicity from treatment with chloramphenicol. Central nervous system toxicities may result from toxic effects of treatment with aminoglycosides but are not related to interactions between the antibiotic and diuretics.
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a. true b. false