Mr. Johnson is a 60-year-old man with severe kidney disease. His kidney disease has caused hypoproteinemia due to the filtration of, and subsequent loss of, protein in the urine. He also has swollen arms and legs. Is it possible that the swollen limbs are linked to his kidney disease?

What will be an ideal response?


Yes. It is possible that the lymph vessels are not able to adequately handle the increased lymph flow that results from hypoproteinemia. Such a condition would cause a decrease in osmotic pressure in the blood and an increase in net filtration in the body's capillaries. This would then overload lymph flow, causing a buildup of lymph and leakage into the interstitial spaces, thereby creating lymphedema.

Anatomy & Physiology

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