A nurse checks the serum digoxin level of a client and finds it to be increased. Which of the following would the nurse identify as possibly associated with this increase?
A) Colestipol (Colestid)
B) Verapamil (Calan)
C) Clarithromycin (Biaxin)
D) Calcium carbonate (Maalox)
E) Spironolactone (Aldactone)
Ans: B, C, E
Feedback:
Increased serum digoxin levels can occur with verapamil, clarithromycin, and spironolactone. Antacids, such as calcium carbonate, and colestipol cause a decrease in serum digoxin levels.
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