Observing replication of circular plasmid DNAs by electron microscopy showed that:

A. replication initiates at multiple origins, creating multiple replication bubbles in the plasmid.
B. template strands completely unwind before replication starts.
C. replication initiates from a single origin, creating a single replication bubble in the plasmid.
D. the plasmid DNA must become linear before replication can initiate at each end of the linear plasmid.
E. replication occurred only at one replication fork of the bubble created.


C

Biology & Microbiology

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