Megaloblastic anemias are caused by a defect in the synthesis of:
a. Deoxyribonucleic acid (DNA)
b. Ribonucleic acid (RNA)
c. Erythropoietin
d. Heme
ANS: A
Defects in DNA synthesis are the cause of most megaloblastic anemias (an exception would be in the myelodysplastic syndrome).
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