A patient who has a diagnosis of schizophrenia is likely to have which of the following pathophysiologic effects?
A) Increased dopamine
B) Increased serum potassium
C) Decreased numbers of glutamate receptors
D) Decreased interaction with GABA
A
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The patient suffering from schizophrenia has increased dopamine activity in the brain. The amount of potassium would cause other physiological symptoms, but not affect schizophrenic symptoms. The patient with schizophrenia will have widespread glutamate receptors, not decreased glutamate receptors. In addition, the glutamatergic system interacts with the dopaminergic and gamma-aminobutyric acid systems and possibly other neurotransmission systems.
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