Major histocompatibility complex (MHC) molecules, with human leukocyte antigens (HLAs), are markers on all nucleated cells and have an important role in:
A) Identifying blood types
B) Cell membrane transport
C) Suppressing viral replication
D) Avoiding transplant rejections
Ans: D
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MHC and HLA markers are unique for each individual, except possibly for identical twins. Tissue and organ transplantation success is dependent on how closely matched the MHC molecules and HLAs are on the donor and recipient. MHC molecules and HLAs are not involved in transport or viral replication. Red blood cells do not have a nucleus and thus do not have HLA or MHC molecules on the surface.
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