Often point mutations can cause a protein to be made that differs in just one amino acid. Which of the following changes is most likely to cause the greatest change in protein function?

A) a mutation that replaces a valine with an isoleucine
B) a mutation that replaces a proline with an aspartic acid
C) a mutation that replaces a glutamic acid with an aspartic acid
D) a mutation that replaces a serine with a cysteine
E) a mutation that replaces an asparagine with a glutamine


Answer: B

Biology & Microbiology

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