Why is it that mutation, acting alone, has little effect on allele frequency, and therefore evolution? What other factors

will magnify the effect? What will be an ideal response?


ANSWER: If the mutation rate for a gene is known, we can use the Hardy–Weinberg formula to
calculate the new allele frequency resulting from mutations in that gene. Let’s use the
dominant trait achondroplasia as an example. For this calculation, we assume that initially
only homozygous recessive individuals with the genotype dd (normal stature) were present in
the population. We will also assume that mutation has added new mutant (D) alleles to each
generation at the rate of 1X10-5. To change the frequency of the recessive allele (d) from 1.0
(100%) to 0.5 (50%) at this rate of mutation will require 70,000 generations, or 1.4 million
years. Our conclusion in this case is that mutation alone has a minimal impact on the amount
of genetic variation present in a population. In other words, mutation generates all new
alleles, but except for very small populations, drift, migration, and selection are the forces
that change the frequency of alleles in a population.

Biology & Microbiology

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You read about how learning preparedness influences the associations that an animal is capable of learning. You want to explore the learning preparedness of hamsters. How might you test the learning preparedness of this species?  

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Biology & Microbiology

What factor accounts for the small size of most

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What was the most significant research finding that resulted from the successful cloning of Dolly?

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Biology & Microbiology