Until recently, only apolipoprotein E (APOE) polymorphisms have been found to correlate with late-onset (nonfamilial) Alzheimer disease (AD); however, these account for less than 50% of the VG. New GWA studies have found a chromosome 12 risk locus
What method will likely be used by AD researchers going forward? A) assessment of chromosome 12 for areas of linkage disequilibrium for AD
B) association of APOE alleles with chromosome 12 SNPs
C) sequencing of candidate genes on chromosome 12 and search for sequence similarity
D) genotyping of a large cohort of AD patients and matched controls using a microchip
E) analysis of genotypes of a large number of AD patients who have none of the expected APOE alleles
D
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Studies of the Pax6 and homologues suggest that the
A. eye has evolved independently multiple times. B. eyes of many different species are descended from a common ancestor. C. master gene of the eye in various species is not homologous. D. eye has evolved independently multiple times and master gene of the eye in various species is not homologous are correct. E. eyes of insects, like Drosophila, derived many times from many ancestors.
Researchers choose a sequence-based evolutionary tree based on which possible tree
A) requires the fewest mutations. B) compares two distant species. C) ignores incomplete datasets in the evaluation. D) is based on molecular clocks and not fossil evidence.
Which of the following organelles is not generally found in animal cells?
A) food vacuole B) centriole C) endoplasmic reticulum D) central vacuole E) mitochondrion
What changes occur in the endometrium as the time of possible fertilization approaches?
A) The endometrium secretes estrogen. B) The endometrium enters the secretory phase. C) The endometrium enters the proliferative phase. D) Menstruation occurs.