Why are sex chromosome aneuploidies less detrimental than autosomal aneuploidies?
A. Sex chromosomes do not contain genes that are important for anything other than sex determination.
B. In females, all but one X-chromosome is inactivated; in males, the Y chromosome contains very few genes, so extra or missing copies do not cause huge abnormalities.
C. Gene expression of the sex chromosomes is not dosage-dependent as it is for the autosomes.
D. Sex chromosomes are only found in gametes, they do not occur in diploid cells.
E. All of these are TRUE.
B. In females, all but one X-chromosome is inactivated; in males, the Y chromosome contains very few genes, so extra or missing copies do not cause huge abnormalities.
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