A client was prescribed alprazolam (Xanax) for symptoms of anxiety related to a recent divorce and relocation. She stated to the nurse, "A little while after I take the medication, I feel out of it and spacey." What is the likely cause of this f
1. The combination of lorazepam with an antidepressant
2. Rapid absorption and distribution to brain cells
3. Sensitivity of the mesencephalic reticular activating system
4. Long elimination half-life
ANS: 2
Xanax and Valium are the two most rapidly absorbed benzodiazepines. The "buzz" effect of feeling spacey is related to CNS depression. 1. The scenario does not mention use of an antide-pressant. 3. This describes the mechanism of barbiturate action. 4. This sensation is not related to half-life.
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