Grapefruit juice contains furanocoumarins that have been found to:
1. Alter absorption of drugs through competition for binding sites
2. Inhibit CYP 3A4, leading to decreased first-pass metabolism of drugs
3. Alter vitamin K metabolism, leading to prolonged bleeding
4. Enhance absorption of calcium and vitamin D
2
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An older adult patient whose medical history includes angina is gardening outside his home when he experiences a sudden onset of chest pain. This patient would most likely administer a dose of nitroglycerin by what route?
A) Subcutaneous injection B) Oral sustained-release tablet C) Nebulized inhalation D) Transmucosal spray
A nurse is preparing to administer an antineoplastic drug that is classified as an antimetabolite. Which of the following might the nurse be preparing to give? Select all that apply
A) Mercaptopurine (Purinethol) B) Capecitabine (Xeloda) C) Fluorouracil (Adrucil) D) Etoposide (Toposar) E) Irinotecan (Camptosar)
A healthcare organization is concerned because several staff members have posted confidential patient information on their Facebook pages. Which should be communicated to all staff regarding the use of social media?
A) Used to post results of diagnostic tests B) Seen as an avenue to report laboratory results C) Used for education and empowerment of consumers D) Encouraged as a way to promote relationships with patients
You check a patient for pain relief 1 hour after administering 15 mg of morphine intramuscularly. The patient is sleeping and has a respiratory rate of 10 breaths/min. What is your best first action?
a. Attempt to arouse the patient by calling his or her name and lightly shaking the arm. b. Administer oxygen by mask or nasal cannula and notify the prescriber. c. Check the patient's oxygen saturation and raise the head of the bed. d. Document the finding as the only action.