Platelets aggregate in response to extrinsic factors that can be described as:
1. Trauma.
2. Bacteria.
3. Antibody?antigen reaction.
4. WBCs.
Trauma.
Rationale: A blood vessel must incur an injury in order for hemostasis to be initiated. Extrinsic factors refer to those outside of the blood vessel, such as an injury.
Bacteria, antibody?antigen reactions, and white blood cells would all represent circulating proteins characteristic of intrinsic factors.
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