Name two types of protein modification that can occur in the ER but not in the cytosol

What will be an ideal response?


1. Proteins in the ER can undergo disulfide bond formation. (This does not occur in the cytosol because of its reducing environment.)
2. Proteins in the ER can undergo glycosylation. (Glycosylating enzymes are not found in the cytosol.)
(Signal-sequence cleavage is also an acceptable answer, although not really what this question is referring to.)

Biology & Microbiology

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