What is the expected result of a "silent" point mutation?
A. Total disruption of the gene reading frame, no production of protein
B. Replacement of one amino acid with another in the final gene product
C. Replacement of an amino acid codon with a "stop" codon, resulting in a truncated protein product
D. No change in amino acid sequence and no change in the composition of the protein product
D
Some amino acids have more than one DNA code or triplet of bases. For example, glycine is coded for by the triplets CCA, CCG, CCT, and CCC. If a mutation in the DNA changed the "normal" triplet for glycine from CCT to CCA, the resulting mutated triplet would still code for glycine. Thus, there would be no amino acid difference in the final protein even though one base was exchanged for another as a result of a mutation in the DNA.
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