An elevation in low-density lipoprotein (LDL) most likely would be related to which comorbid condition?
1. Diabetes mellitus
2. Renal insufficiency
3. Iron-deficiency anemia
4. Hyperthyroidism
Correct Answer: 1
Rationale 1: Clients with diabetes mellitus require more aggressive therapy to reduce the risk of atherosclerosis.
Rationale 2: Cholesterol is excreted from the liver through the biliary tract, so diminished renal function has no effect on lipid levels and atherosclerosis risk.
Rationale 3: There is no association between iron-deficiency anemia and elevated LDL levels, but LDL levels might be decreased if the iron deficiency is severe.
Rationale 4: Hyperthyroidism increases the rate of lipoprotein metabolism, which would lead to a decrease in LDL levels.
Global Rationale: Clients with diabetes mellitus require more aggressive therapy to reduce the risk of atherosclerosis. Cholesterol is excreted from the liver through the biliary tract, so diminished renal function has no effect on lipid levels and atherosclerosis risk. There is no association between iron-deficiency anemia and elevated LDL levels, but LDL levels might be decreased if the iron deficiency is severe. Hyperthyroidism increases the rate of lipoprotein metabolism, which would lead to a decrease in LDL levels.
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