A patient is a gravida 1, Rh-negative woman at a 28 weeks' gestation. The father of her child is Rh positive. The mother is asking the nurse about the effect on her unborn child of RhoGAM that has been ordered. What is the nurse's best reply?

a. "Your child will do well after birth once transfusions are administered."
b. "If the baby is Rh negative at birth, he or she will need RhoGAM also."
c. "RhoGAM kills antibodies you make, so your child will be protected."
d. "Your baby may be Rh positive and cause you to make antibodies. These won't affect this baby but could affect future children if RhoGAM isn't given."


ANS: D
An Rh-negative mother and an Rh-positive father have the potential for an Rh-positive baby. At birth or during any time that the uterus ruptures, fetal blood circulation can mix with maternal circulation, causing the mother to produce antibodies (active immunity) against Rh-positive blood. This would cause Rh hemolytic disease in children of future pregnancies. Rho(D) immune globulin suppresses the stimulation of active immunity by Rh-positive foreign red blood cells that enter maternal circulation at the time of delivery, at the termination of pregnancy, or during a transfusion of inadequately typed blood. Transfusions may cause further problems. Immune globulin is given to the mother. The drug does not kill antibodies; it suppresses production.

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