A 42-year-old man suffering from recurrent urinary stones was found to have hypercalcemia, hypophosphatemia, and high blood levels of parathyroid hormone. An exploratory neck dissection revealed the most common cause of this condition
What is the most likely diagnosis?
A. parathyroid adenoma
B. parathyroid carcinoma
C. primary parathyroid hyperplasia
D. secondary parathyroid hyperplasia
E. tertiary parathyroid hyperplasia
A
Parathyroid adenoma in one of the four glands is the most common cause of hyperparathyroidism and is found in 80% of such patients. Primary hyperplasia of the parathyroids involving all four glands and parathyroid carcinoma are less common. Laboratory findings do not support the diagnosis of secondary or tertiary hyperparathyroidism.
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