Which of the following is a feature of malignant cells in fluids?
a. Small size
b. Three-dimensional clumps with no "windows"
c. Low nuclear-to-cytoplasmic (N:C) ratio
d. Uniformity
ANS: B
Mesothelial cells are the lining cells of body cavities and are shed into these cavities. They can be confused with malignant cells. However, when mesothelial cells appear in clumps (a frequent occurrence), usually windows are noted between the cells. This is not true of malignant cells that are also commonly found in clumps.
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