A patient tells the nurse that she takes aspirin for menstrual cramps, but she does not feel that it works well. What will the nurse suggest?
a. The patient should avoid any type of COX inhibitor because of the risk of Reye's syndrome.
b. The patient should increase the dose to a level that suppresses inflammation.
c. The patient should use a first-generation nonsteroidal anti-inflammatory medication instead.
d. The patient should use acetaminophen because of its selective effects on uterine smooth muscle.
ANS: C
Aspirin (ASA) has analgesic effects for joint pain, muscle pain, and headache, but it is relatively ineffective against visceral pain, including uterine smooth muscle pain, for which NSAIDs are indicated. The risk of Reye's syndrome is associated with the use of ASA in children to treat fever. Increasing the ASA dose to anti-inflammatory levels is useful for rheumatic fever, tendonitis, and bursitis. Acetaminophen is not effective for dysmenorrhea.
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