With respect to a gene with two alleles, for each generation of complete inbreeding the proportion of heterozygotes is expected to be reduced by while the proportion of each homozygous class is expected to increase in frequency by

Explain why this is so.


The three genotypes for our two-allele gene are AA, aa, and Aa. Complete inbreeding for AA and aa will yield the same genotypes. Each cross of Aa × Aa, however, will yield AA, Aa, and aa in a 1:2:1 ratio [ : : ]. Thus, the heterozygotes are reduced by , while each homozygous class increases by .

Biology & Microbiology

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