The nurse is teaching a class to a community group about peptic ulcer disease. Which statement about the use of anticholinergics for PUD is correct?
a. "Because very high doses of these drugs are needed to inhibit acid secretion, the side effects usually are unacceptable to those taking the drug."
b. "Anticholinergics can cause diarrhea, glucose intolerance, and dehydration."
c. "Anticholinergics are the drugs of choice for most patients with peptic ulcer dis-ease."
d. "Anticholinergics can cure PUD when used as single-agent therapy."
A
The doses of anticholinergics required to inhibit acid secretion are so high they produce musca-rinic blockade throughout the body, which leads to dry mouth, constipation, urinary retention, and visual disturbance. These side effects can be very disturbing.
Anticholinergics cause constipation, not diarrhea. Dehydration and glucose intolerance are not side effects of anticholinergics.
Anticholinergics are rarely used for treatment of PUD because of their side effects.
No single agent alone is recommended for the treatment of PUD. In addition, the cause of the ulcer must be identified so that an appropriate treatment plan is selected.
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