A B cell's sensitivity to antigen can be increased 1000–10,0000-fold by
a. simultaneously ligating the B-cell receptor and co-receptor
b. simultaneously ligating the B-cell receptor and Toll-like receptor
c. ligating the B-cell co-receptor and phosphorylating Ig-? ITAMs
d. increasing levels of Syk proteins in the vicinity of co-receptor ligation
e. ligating cytokine receptors on the B-cell surface.
A
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