Which preparation of antidiuretic hormone (ADH) is occasionally used by the intranasal route to treat enuresis?
1. Lypressin (Diapid)
2. Vasopressin (Pitressin)
3. Betamethasone (Celestone)
4. Desmopressin (Stimate)
Correct Answer: 4
Rationale 1: Lypressin (Diapid) is incorrect because Diapid and Pitressin are used to treat diabetes insipidus.
Rationale 2: Vasopressin (Pitressin) is incorrect because Diapid and Pitressin are used to treat diabetes insipidus.
Rationale 3: Betamethasone (Celestone) is incorrect because Celestone is a glucocorticoid.
Rationale 4: ADH conserves water in the body. It is secreted from the posterior pituitary gland, and acts on the collecting ducts in the kidney to increase water reabsorption. A deficiency of ADH known as diabetes insipidus causes the client to lose large volumes of water. A theory of treatment for enuresis is that these clients might benefit from ADH preparations for bladder control.
Global Rationale: ADH conserves water in the body. It is secreted from the posterior pituitary gland, and acts on the collecting ducts in the kidney to increase water reabsorption. A deficiency of ADH known as diabetes insipidus causes the client to lose large volumes of water. A theory of treatment for enuresis is that these clients might benefit from ADH preparations for bladder control. Lypressin (Diapid) is incorrect because Diapid and Pitressin are used to treat diabetes insipidus. Betamethasone (Celestone) is incorrect because Celestone is a glucocorticoid.
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