A mechanism by which cancer cells can evade an immune response involves an alteration in the amount of MIC on the cell surface by
a. decreasing the level of MIC transcription
b. cleavage of MIC at the cell surface by a protease
c. switching from a transmembrane form of MIC to a secreted form
d. cytosolic degradation of MIC in proteasomes
e. alternative mRNA splicing resulting in a truncated form of MIC that is no longer able to bind to NKG2D.
B
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