A male patient has a history of a genetic disorder and is concerned that this same disorder will be passed to his children. What information should the nurse provide to this patient?
1. All genetic disorders are passed to future children.
2. If the genetic disorder is a disorder of metabolism, it will most likely not be passed to any children.
3. The best possible plan for this problem is to avoid children.
4. The children will inherit the disorder only if the disorder is on chromosomes 13, 18, and 21.
Correct Answer: 2
Mitochondrial genes and any diseases due to DNA alterations on those genes are transmitted through the mother in a matrilineal pattern. An affected female will pass the metabolism DNA mutation to all of her children. An affected male will not pass the metabolism DNA mutation to any of his children. It is inappropriate for the nurse to recommend the patient not have children. This recommendation steps beyond the scope of practice. Inherited disorders exist beyond those involving chromosomes 13, 18, and 21.
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