The patient comes to the emergency department after an overdose of lorazepam (Ativan). The nurse will plan to administer which medication?
1. Pralidoxime (Protopam)
2. Naloxone (Narcan)
3. Flumazenil (Romazicon)
4. Nalmefene (Revex)
Correct Answer: 3
Rationale: Should an overdose of benzodiazepines occur, flumazenil (Romazicon) is a specific benzodiazepine receptor antagonist that can be administered to reverse central nervous system (CNS) depression. Naloxone (Narcan) is indicated for treatment of opiate overdose. Nalmefene (Revex) is indicated for treatment of opiate overdose. Pralidoxime (Protopam) is indicated for treatment of organophosphate poisoning.
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