Answer the following statement(s) true (T) or false (F)

Question

1. Warfarin is the anticoagulant of choice because it has so few interactions with other
medications.
2. Niacin should be discontinued immediately if the patient complains of skin flushing because
this indicates a serious allergic reaction.
3. Fenofibrates are considered a good choice for reducing LDL in diabetes because they
improve glucose tolerance.
4. Warfarin and heparin are useful in dissolving blood clots to prevent embolization.
5. Protamine is used to completely reverse the activity of LMWHs.

Answer 1

1. False
Warfarin actually has multiple medication, food, and herball interactions that must be considered during therapy.
2. False
Flushing is to be expected with niacin and may be avoided or minimized by pretreatment with aspirin or ibuprofen.
3. True
4. False
These medications only interfere with the coagulation process to
prevent clot formation and propagation they are not thrombolytics.
5. False
No agent fully reverses the activity of LMWHs; however, protamine
may be useful for reversal when given along with PRBCs and FFP.