For each statement below, indicate whether it is true or false, and explain why

A. To meet a challenge or develop a new function, evolution essentially builds from first principles, designing from scratch, to find the best possible solution.
B. Nearly every instance of DNA duplication leads to a new functional gene.
C. A pseudogene is very similar to a functional gene but cannot be expressed because of mutations.
D. Most genes in vertebrates are unique, and only a few genes are members of multigene families.
E. Horizontal gene transfer is very rare and thus has had little influence on the genomes of bacteria.


A. False. Evolution can work only by tinkering with the tools and materials on hand, not by starting from scratch to make completely new genes or pathways. New functions arise from the ancestral functions by a process of gradual mutational change, and thus may not represent the best possible solution to a problem.
B. False. Many duplications are subsequently lost or become pseudogenes, and only a few evolve into new genes.
C. True. Pseudogenes look very similar to normal genes but cannot produce a full-length protein, as a result of one or more disabling mutations.
D. False. A large proportion of the genes in vertebrates (and many other species) are members of multigene families.
E. False. By some estimates, 20% of the genomic DNA in some bacterial species arose by horizontal gene transfer.

Biology & Microbiology

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Biology & Microbiology